Travis Kelce has been a thorn in the Chargers for years. The Chiefs have dominated the Chargers in Kelce's career. Kelce has shown the Chargers respect.

Preview the Week 15 matchup between the Kansas City Chiefs and Los Angeles Chargers with predictions, odds, over/under, spread, betting lines and more.

Going with KC are five of six USA Today writers: Jarrett Bell (27-24 final score), Chris Bumbaca (24-21), Nate Davis (24-20), Tyler Dragon (26-23) and Michael Middlehurst-Schwartz (24-21). Picking the Chargers is Nick Brinkerhoff (27-23).

But the fact some sportsbooks have the Chargers as bigger and bigger underdogs as the week progresses is pretty, well, interesting. Most outlets had the Chargers as underdogs by less than a touchdown to start the week. But it’s a number that has slowly crept closer and closer to the touchdown mark before kickoff.

Khalil Mack looks forward to the challenge: "Not as much so the feeling of beating them, but knowing what beating them can do for us."

Everything you need to know about the Chargers vs. the Kansas City Chiefs on Sunday, including how to watch, odds and a prediction on who will win.

This article was originally published on www.si.com/nfl/chargers/onsi as Chargers warned stumble vs. Chiefs could lead to missing playoffs. The Los Angeles Chargers sit in the driver’s seat for an NFL playoff berth entering the Week 15 game against the Kansas City Chiefs.

The Los Angeles Chargers and Kansas City Chiefs battle in Week 15 of the 2025 NFL season with Kansas City's playoff hopes hanging in the balance while the Chargers remain in contention for the AFC West division title. These teams met in Week 1 in Brazil, with the Chargers registering a statement win with a 27-21 result.