Learn more > The 49ers host the Jaguars in a Week 4 matchup of the 2025 NFL season at Levi's Stadium on Sunday.

The San Francisco 49ers and Arizona Cardinals get together Sunday in Santa Clara for a key Week 3 battle of NFC West unbeatens.

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The San Francisco 49ers begin their quest to a Supe Bowl with the season-opener against the Seattle Seahawks today. Find out how to watch this NFL game for free.

The San Francisco 49ers never really got going in their Week 4 loss vs. the Jacksonville Jaguars. Here are the highlights.

49ers Interior Defensive Line Earn 'Shakiest' Unit in ESPN Rankings originally appeared on Athlon Sports. The San Francisco 49ers are fresh off an injury-plagued 2024 campaign that saw just six wins and a last-place finish in the normally competitive NFC West.

The South Florida Bulls play against the Charlotte 49ers in a college football game tonight. Fans can watch this game for free online.

On a 3rd-and-5, Ferguson ran a slot fade vs. man coverage and elevated over a safety to haul in his first career reception for a 21-yard gain. It was the same route he caught a pass on in his preseason debut against the Browns, but this one was a bit underthrown, and he had to adjust to make the grab.

The Jacksonville Jaguars will face the San Francisco 49ers in Week 4 of the NFL season on Sunday at Levi's Stadium.