The San Francisco 49ers beat the Los Angeles Rams in what looked like an improbable outcome. San Francisco was far more shorthanded than their division rivals due to injuries, but still pulled off the upset. While the team is going to be happy with the win, they will have to evaluate a new slew of injuries .

San Francisco 49ers tight end George Kittle is eligible to be activated off injured reserve to play in the team's Week 6 matchup with the Tampa Bay Buccaneers, but that doesn't necessarily mean a return will happen against Tampa Bay.

San Francisco 49ers quarterback Brock Purdy is officially out for "Thursday Night Football" against the Los Angeles Rams with a toe injury. Mac Jones is expected to start in Purdy's place.

The injury-ravaged San Francisco 49ers will again be missing multiple starters with injuries for the Thursday night game against the Los Angeles Rams.

Here is a closer look at the 49ers' injuries, how the team has been impacted in comparison to other NFL franchises and a year-by-year timeline of absences to key players.

San Francisco 49ers edge rusher Nick Bosa suffered a serious knee injury in the Week 3 game against the Arizona Cardinals, but will he be able to return this season. Here's what we know.

Eagles WR A.J. Brown is publicly frustrated with the team about his lack of targets. Could the 49ers acquire him with this trade package?