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Rams, San Francisco 49ers and Thursday Night Football

Thursday Night Football prediction, odds, spread, bets, line: Rams vs. 49ers picks from expert on 25-10 roll

Early control of the NFC West will be on the line when the San Francisco 49ers take on the Los Angeles Rams on Thursday Night Football.

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Rams vs. 49ers 2025 Prediction, Odds, Picks - Oct 2

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Thursday Night Football predictions, picks, odds for Rams vs 49ers NFL Week 5 game today

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Best NFL Picks and Predictions Today (How to Bet 49ers vs. Rams on Thursday Night Football in NFL Week 5)

First place in the NFC West is up for grabs on Thursday night in Week 5, as the San Francisco 49ers hit the road to take on the Los Angeles Rams in a battle of 3-1 teams.

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5 quick takeaways from Jaguars first 4 games of NFL season

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What time is the NFL game tonight? TV schedule, channel, live stream to watch Rams vs. 49ers in Week 5

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Rams vs. 49ers anytime touchdown scorer picks, predictions, betting odds: Target Kyren Williams on TNF

The SportsLine Projection Model has locked in its top anytime TD scorer picks for San Francisco vs. Los Angeles on Thursday Night Football

USA TODAY Touchdown Wire on MSN

49ers fix huge roster issue, swap 2 picks for Saints $52 million DE in projected NFL trade

Sigler projected the 0-4 Saints to quickly become sellers ahead of the Nov. 4 trade deadline. One of his potential moves has the 49ers sending third and fourth-round picks in the 2026 draft to New Orleans in exchange for 28-year-old Northern California native Carl Granderson.