Since sustaining the injury during the first week of the NFL season, Kittle has been placed on injured reserve.

San Francisco 49ers star George Kittle will likely miss Week 6. His return from a hamstring injury is now a long shot for the upcoming game. Coach Kyl

The Falcons have seen a tremendous year-over-year improvement from their defense, but their post-bye week showdown with the Bills will be its biggest test yet.

The Falcons' next two opponents after their bye are the first-ranked Buffalo Bills and the San Francisco 49ers, who sit at No. 8 in Pro Football Focus' Week 5 power rankings. If Atlanta can manage a win against either of those teams, its a strong indication as to where the team is currently.

The 49ers and Rams are battling for control of the NFC West on "Thursday Night Football." Here's where to watch the divisional rivals face off.

Mike Florio and Chris Simms preview a Week 5 Sunday Night Football showdown between the Patriots and Bills at Highmark Stadium, analyzing a shocking spread and sharing why Josh Allen's squad is on upset alert at home.

Christian McCaffrey and the San Francisco 49ers face Puka Nacua and the Los Angeles Rams on Thursday Night Football in Week 5 of the NFL season at SoFi Stadium.