Los Angeles Rams inside linebacker Nate Landman (0:00), outside linebacker Byron Young (1:15), wide receiver Davante Adams (2:55), running back Kyren Williams (4:54), and wide receiver Puka Nacua (6:51) react to tonight's loss to the San Francisco 49ers.

The 49ers defeated the Rams 26-23 in overtime behind a terrific performance from Mac Jones, another workmanlike effort from Christian McCaffrey, a career night from Kendrick Bourne and several clutch red zone plays from their defense.

Kyren Williams fumbles the ball at the goal line late in regulation and can't convert on fourth down in overtime in the Rams' 26-23 loss to the 49ers.

Los Angeles Rams quarterback Matthew Stafford's best throws from his three touchdown game vs. the San Francisco 49ers during Week 5 of the 2025 NFL season.

Follow along for live updates from the Los Angeles Rams' Week 5 game against the San Francisco 49ers on Thursday Night Football.