The population of older adults at risk for thromboembolic disease, including venous thromboembolism and systemic thromboses, is rapidly expanding because of increased longevity and improved therapy ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the neurochemical ...

Patients with atrial fibrillation (AF) have an increased risk of negative clinical outcomes. In this review article, physicians from the Chinese Academy of Medical Sciences and Peking Union Medical ...

Anticoagulant rodenticides have long been the cornerstone of rodent pest management. Their mode of action centres on inhibiting the vitamin K epoxide reductase complex, with the VKORC1 gene encoding ...

Anticoagulant treatments are crucial for managing many conditions, such as heart disease, stroke and venous thrombosis. Current options, however, carry an inherent risk of serious bleeding due to ...