Scientists discover how innate immunity envelops bacteria. The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites ...

Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the GI tract. The two major types of IBD are Crohn's disease (CD) and ulcerative colitis (UC). Whereas in UC inflammation ...

Review of the emerging understanding of trained immunity in the skin and how infection-driven cellular processes induce long-lasting immune adaptation and modulate skin barrier integrity.

The Cullin family proteins have been shown to act as internal components of the ubiquitin-proteasome system, mediating the signaling pathways for protein degradation and the maintenance of cellular ...

Much like humans generate mountains of garbage, our cells are constantly discarding proteins that are damaged or no longer needed. The cellular waste disposal system called the proteasome is best ...

Much like humans generate mountains of garbage, our cells are constantly discarding proteins that are damaged or no longer needed. The cellular waste disposal system called the proteasome is best ...

The World Health Organization estimates that 1.27 million people died directly from drug-resistant bacterial strains in 2019 and these strains contributed to 4.95 million deaths. While bacteria ...

The human body’s defensive lineup is impressive—from made-to-order antibodies to natural-born killers. Here’s how it wards off sickness in every season. When pathogens invade our bodies—in the form of ...

Antimicrobial overuse in agriculture can drive the evolution of bacteria more resistant to the first line of human defences, warned scientists. Antimicrobial resistance "threatens" the very core of ...