It's a busy uniform slate in Week 5 of the NFL season, led by the Buffalo Bills debuting their Rivalry threads.

Expert recap and game analysis of the Buffalo Bills vs. New Orleans Saints NFL game from September 28, 2025 on ESPN.

Our two team reporters are at MetLife Stadium and they're keeping you updated on all the biggest plays and highlights.

The 41-year-old made his Bills debut, replacing Tyler Bass, who’s on injured reserve with hip and groin issues. Buffalo ...

Bosa is not the first highly regarded veteran pass rusher to enter One Bills Drive. The Bills signed Von Miller to a six-year ...

Though small sample size, Cook has played in 56.2% of the Bills' snaps, including those negated by penalties, up from 47.5% ...

The Bills were going to rely on new leaders and a new offensive room without a traditional No. 1 receiver. They went on to set franchise records in points (525) and touchdowns (65). The team finished ...

The Bills struggled to get off the field as Miami converted 10 of 15 third-down opportunities, including a variety of ...

NFL survivor pool strategy, predictions and picks for ESPN Eliminator Challenge Week 4, including teams to pick or save for ...

Ravens quarterback Lamar Jackson will not face discipline from the NFL for his altercation with a Buffalo Bills fan during a ...

The NFL made the "sack" stat official in 1982. Check out which NFL players and teams have the most sacks in a game now.