Preview the Week 12 matchup between the Buffalo Bills and Houston Texans with predictions, odds, over/under, spread, betting lines and more.

The Texans mounted an impressive comeback against the Jacksonville Jaguars in Week 10 and found a way to win in Tennessee last Sunday despite not scoring a single point in the first half, but the Bills are a different kind of test. Buffalo covers the spread in prime time. Pick: Bills -5.5; Under 43.5

NFL Week 12 odds, picks, predictions, TV channel, streaming information for the Thursday Night Football game between Buffalo Bills and Houston Texans.

In a game in which the lead changed hands nine times, the Bills scored two fourth-quarter touchdowns for a 44-32 win at Highmark Stadium, thwarting a Bucs effort that included 202 rushing yards and th

Josh Allen almost made an incredible play to convert a third-and-16. He took off down the field after escaping from pressure and tried to lateral the ball to Ty Johnson, but his "backwards" pass actually traveled forward so the Bills were penalized five yards from the spot of the foul and had to punt. They downed the ball at the 3-yard line.

Tucker’s six-yard TD run in the third came after Mecole Hardman fumbled a punt at the Buffalo 43, and after a Matt Prater field goal, the Bills regained the lead as Cole Bishop’s interception at the Bucs 25 was followed on the next snap by Allen’s TD pass to James Cook for a 31-26 lead.

The Buffalo Bills return to action on a short week as they head to NRG Stadium for a Week 12 Thursday night matchup against the Houston Texans, with kickoff set for 8:15 p.m. Buffalo enters at 7-3 after a 44-32 win over the Tampa Bay Buccaneers.

The Bills truly need to win this game to stay relevant in the AFC East, a division which has seen the England Patriots dominate this season. After a billion years of hearing that phrase, Bills fans don’t feel like they’ve had enough time on top to make up for the dynasty that was the Patriots.

The Buffalo Bills host the Tampa Bay Buccaneers in a vital game at Highmark Stadium. Here is Sal Maiorana's preview and prediction.

ORCHARD PARK, N.Y. — Coming off a humbling loss last week, the Buffalo Bills returned home to deliver a helter-skelter 44-32 statement win over the NFC South-leading Tampa Bay Buccaneers, a game that featured nine lead changes.