Senescent cells are intrinsically immunogenic and can be eliminated by the immune system to facilitate tissue repair and regeneration. However, immune-mediated elimination is compromised with age, ...

Antibody-mediated rejection (ABMR) remains the leading immunological cause of kidney allograft loss, yet its humoral origins are incompletely understood.

The adaptive immune system of vertebrates represents a major evolutionary innovation that underpins the capacity for antigen-specific recognition, immunological memory and refined regulation of host ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...