Centrosomes are not essential for cell division in most animal cells, although they contribute to the efficiency of mitotic spindle assembly. Centrosome loss is tolerated surprisingly well in fly ...

Centrosomes are small structures in cells with many essential functions, including roles in cell signaling and in organizing a cell’s cytoskeleton. Centrosome dysfunction contributes to diseases like ...

A basic requirement for growth and life of a multicellular organism is the ability of its cells to divide. A protein complex, the so-called centrosome, plays a major role during cell division.

The cover for issue 26 of Oncotarget features Figure 6, "Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells," by Osman, et al. and reported that ...

A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8+ T cell division for the generation of memory precursor cells.

Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside cells called centrioles, revealing a mechanism linked to developmental ...

Understanding cell biology at the molecular level necessitates the careful characterization of protein function. It would be very convenient if one gene resulted in one protein that had one function, ...