A study published in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

Cross-species research shows that RNA splicing patterns, not just gene activity, track maximum lifespan in mammals, revealing ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Researchers at Pohang University of Science and Technology (POSTECH) have built a platform that steers cell behavior using ...

It could be simply to control gene expression." The study, "Global impact of unproductive splicing on human gene expression levels and traits," was supported by funding from the National Institutes of ...

A new software package called CREsted, published in Nature Methods, gives researchers an end-to-end workflow for modeling and ...

Our circadian clocks play a crucial role in our health and well-being, keeping our 24-hour biological cycles in sync with light and dark exposure. Disruptions in the rhythms of these clocks, as with ...

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of lncRNAs ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...