DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning organism also requires precise instructions about when, where, and how ...

Our DNA is under constant threat. Chemicals, radiation and the everyday errors of cell division all damage it, and if left ...

Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes ...

The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a ...

Artificial intelligence has just redrawn the map of our genome’s control room, revealing hundreds of thousands of tiny DNA knots that behave less like static quirks and more like hidden switches.

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...

The human genome is chock full of what scientists once considered "junk DNA." This DNA is actually something called transposable elements, or TEs. These are repetitive sequences found in the genome ...

e2MPRA allows researchers to introduce any nucleotide substitutions across regulatory sequences and assess their variant effects on gene expression, DNA accessibility, and epigenetic modifications at ...