San Francisco 49ers WR Kendrick Bourne posts career-best game in Thursday Night Football overtime win vs. Los Angeles Rams.

SERIES RECORD: 49ers lead 19-14-1. LAST MEETING: 49ers defeated the Eagles 17-11 on Sept. 9, 2021, in Philadelphia. LAST WEEK: 49ers defeated Cowboys, 19-12; Eagles beat Giants, 38-7. EAGLES OFFENSE: OVERALL (3), RUSH (5), PASS (9), SCORING (3). EAGLES ...

Christian McCaffrey achieved a historic milestone in his 100th career NFL game in the San Francisco 49ers' win over the Los Angeles Rams on Thursday.

Week 5's Thursday Night Football matchup between the Rams and 49ers will air live on Amazon Prime Video. The action will not be available on traditional TV. NFL fans can tune into the Rams vs. 49ers game live on SiriusXM channels 225 (Rams) and 226 (49ers).

Los Angeles fell in overtime at home to their division rivals, but the quarterback’s wife at least had a winning look.

The NFL announced Monday that the Tampa Bay Buccaneers’ Week 6 game has been moved to the late afternoon window.The Buccaneers’ game against the San Francisco 49ers on Oct. 12 has been flexed to a 4:25 p.

The Philadelphia Eagles keep finding ways to win. The Denver Broncos are aiming to hand them that first loss. Coming off a lopsided rout over Cincinnati on Monday night, the Broncos (2-2) have a tough challenge with a short turnaround going to face the reigning Super Bowl champs.

While several teams fell from the ranks of the undefeated Sunday, Philadelphia won its 18th straight game with Jalen Hurts under center.

San Francisco 49ers quarterback Brock Purdy is once again dealing with a toe issue after returning to the lineup on Sunday.

Be sure to check out DraftKings for all the latest game odds & team props for every matchup this week on the NFL schedule! Josh Allen O/U 0.5 Interceptions vs Patriots. Josh Allen