Anne van Schoonhoven is in the Departments of Pulmonary Medicine and of Cell Biology, Erasmus University Medical Center, Rotterdam 3015 GD, the Netherlands. Ralph Stadhouders is in the Departments of ...

For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in ...

CRISPR gene editing has transformed research, but it is not perfect, and can sometimes target unintended genes; to watch CRISPR enzymes respond to different genes, Leipzig University researchers ...

DNA is the genetic material used by every living organism. But, in a few edge cases, the four bases of DNA—adenine, thymidine, cytosine, and guanine—undergo chemical modifications. And in viruses, ...

CAMBRIDGE, MA -- Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way. Using this system ...

Genomic alteration using adenine base editors demonstrated the most potency in restarting fetal hemoglobin expression in cells of patients with sickle cell disease, study results showed. The genome ...

The remarkable genetic scissors called CRISPR/Cas9, the discovery that won the 2020 Nobel Prize in Chemistry, sometimes cut in places that they are not designed to target. The remarkable genetic ...