Meiotic recombination frequency varies along chromosomes and strongly correlates with sequence divergence. However, the causal relationship between recombination landscapes and polymorphisms is ...

Epigenetic inheritance and cellular memory hinder removal of intrinsic epigenetic marks, hampering exploration of the fundamental principles behind their establishment. We developed SynNICE for the de ...

A team of Chinese researchers has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems. Subscribe to our newsletter for the latest sci ...

For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in the genetic code. Arc Institute researchers are changing that paradigm with ...