Synthetic hydrogel-based assay to study 3D confined cell migration. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adm9195 Eukaryotic cells—that is, cells with a nucleus—possess an astounding ...

Imagine cells navigating through a complex maze, guided by chemical signals and the physical landscape of their environment. A team of researchers at the University of Maryland, Baltimore County (UMBC ...

Migrating cells must determine where to form a front end and a back end. A gradient in contact sites between the cell membrane and an organelle called the endoplasmic reticulum (ER) is generated by a ...

The cells in our bodies move in groups during biological processes such as wound healing and tissue development—but because of resistance, or viscosity, those cells can't just neatly glide past each ...

Shootin1b and the adhesion molecule transmit weak traction forces which is well-suited for rapid cell migration, presenting a potential target for preventing spread of glioblastoma. "By suppressing ...

Immune responses rely on the efficient movement of immune cells within the complex and geometrically unpredictable three-dimensional tissues that make up our bodies. Subscribe to our newsletter for ...

How do cells move from A to B through our body to build functional tissues? And how is this process regulated? The answers to these questions are essential – for example, for our understanding of how ...

Ikoma, Japan—Ever wondered how the different cells in our body communicate with each other to fulfill their different roles—be it cells repairing a tissue injury or immune cells moving towards an ...

“Why are the cells growing there?” Why, indeed. Why would cancer cells migrate to the spinal fluid, far from where they’d been birthed, and how did they manage to thrive in a liquid so strikingly poor ...

The gastrointestinal tract is the biggest immune organ in mammals. The gut extends its influence all over the body through various links like the gut-liver axis, the gut-lung axis, and the gut-brain ...

Scientists are looking for answers about how these confounding trips, known as metastases, occur throughout the human body Illustration of a human cancer cell Amber Dance, Knowable Magazine Back in ...