“This is an early but exciting step toward recharging aging tissues using their own biological machinery,” Gaharwar says in ...

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...

They fall into the following main categories: mitochondria-targeted antioxidants, modulating mitochondrial dynamics, enhancing mitochondrial quality control, potentiating mitochondrial biogenesis, ...

Mitochondria are incredible organelles. They not only provide crucial power to our cells, but these little machines also have their own tiny little genomes, and can even make their own proteins. But ...

More than 150 human diseases — including Lou Gehrig’s, Parkinson’s and Alzheimer’s — are linked to mitochondrial failure, and one Nebraska scientist is working to decode why. A five-year, $2 million ...

A long-studied metabolic hormone, FGF21, also acts as a stress hormone—a discovery that helps explain how psychological stress causes metabolic dysregulation and drives physical disease, according to ...

When doctors prescribe oxybutynin, it's usually for an unglamorous problem: bladder incontinence. But researchers have discovered a surprising new role for this decades-old drug—one that could open ...

Area of Focus: mitochondrial quality control, cellular metabolism, immune responses and the mechanisms underlying neurodegenerative diseases. Fourteen years ago, Xin Qi joined the Department of ...

When you buy through links on our articles, Future and its syndication partners may earn a commission. POLG-related diseases are a diverse family of conditions all caused by mutations in a gene for a ...

As of 2019, about 4.9 million people globally were living with an inflammatory bowel disease (IBD) such as Crohn’s disease. Scientists are still unclear as to the exact cause of Crohn’s disease, which ...

YOU MIGHT KNOW them as the “powerhouses of the cell,” but that’s selling mitochondria short—these microscopic MVPs play a role in almost everything that makes you healthy. With the right lifestyle ...