As for the Cardinals, their running back contingency plan is being tested. James Conner is out for the year, which opened the door for second-year back Trey Benson. Unfortunately for the Cards, Benson injured his ankle last week, so Michael Carter and Emari Demercado are expected to get the bulk of the touches out of the backfield moving forward.

WHERE: Bank of America Stadium (Charlotte, N.C.) WHERE: MetLife Stadium (East Rutherford, N.J.) WHERE: State Farm Stadium (Glendale, Ariz.)

Keep up with the 2025 NFL season on FOX Sports. Prior to the final injury report, which lists players as questionable, doubtful or out, NFL teams use practice designations to update player injury statuses. This can include DNP (did not participate), LP (limited participant) or FP (full participant).

Here's a look at the initial injury reports for Week 5 and the final designations for 'Thursday Night Football'

The Bills added defensive tackle T.J. Sanders and cornerback Dorian Strong to their injury report ahead of their clash with the Patriots.

NFL Insider Tom Pelissero gives an injury update on Washington Commanders quarterback Jayden Daniels and wide receivers Terry McLaurin and Deebo Samuel ahead of their Week 5 matchup against the Los Angeles Chargers.

The Washington Commanders are set to be without two of their top offensive playmakers in quarterback Jayden Daniels and wide receiver Terry McLaurin. The San Francisco 49ers received some good news with quarterback Brock Purdy set to return, and the Rams will have to wait and see if veteran wideout Davante Adams can give it a go.

The 49ers are dealing with numerous injuries heading into their Week 5 "Thursday Night Football" matchup with the Rams. Here's a look at all of them.

Week 5 of the NFL season is upon us, with fantasy managers likely scrambling to make adjustments with all of the injuries across the league.

CINCINNATI — The Bengals are taking on the Detroit Lions this weekend without two contributors in the fold. Rookie defensive end Shemar Stewart (ankle) is out for the NFC-AFc matchup. Meanwhile, wide receiver Charlie Jones (Achilles) is questionable. Zac Taylor confirmed their statuses following Friday's walkthrough.

A new addition to the injury report for the TCU side is defensive lineman Ansel Din-Mbuh, who played in last week’s game against Arizona State. The Washington State transfer has played well for the Horned Frogs,