The outlook for some 3 million people with narcolepsy worldwide could soon improve as drugmakers are racing to win approval of a new class of drugs.

New research has found that people with narcolepsy type 1 exhibit patterns of slow brain pulsations that resemble those seen in healthy sleep. The findings, published in PNAS, suggest that orexin—a ...

A hormone produced by the brain, orexin, may play a central role in the functioning of the brain's glymphatic system, which clears waste, according to a new study from the University of Oulu.

Narcolepsy affects how you sleep and stay awake. You can feel very sleepy during the day and may suddenly fall asleep without warning. Narcolepsy symptoms can come and go or change over time. Some ...

Alkermes ALKS announced positive top-line data from the phase II Vibrance-1 study, which evaluated its novel, investigational, and oral orexin 2 receptor agonist, alixorexton (formerly ALKS 2680), for ...

Patients with narcolepsy have a significantly greater risk for cardiovascular disease (CVD) and major adverse cardiovascular events (MACE), even after accounting for stimulant use. These findings were ...

Elaine Chen covers biotech, co-writes The Readout newsletter, and co-hosts STAT’s weekly biotech podcast, The Readout Loud. You can reach Elaine on Signal at elaineywchen.70. Alkermes and Takeda ...

DUBLIN, Aug. 25, 2025 /PRNewswire/ -- Alkermes plc (Nasdaq: ALKS) today announced plans to present detailed results from its Vibrance-1 phase 2 study evaluating alixorexton in patients with narcolepsy ...

Because of narcolepsy, Green Bay Packers defensive tackle Nazir Stackhouse sometimes fell asleep during games at Georgia. With different medication, “Big Sleepy” is in position to challenge for a ...