New England Patriots offensive coordinator Josh McDaniels has been around the block in the AFC East. McDaniels, 49, is a longtime coach of the Pats, serving in

It's the New England Patriots vs Buffalo Bills this Sunday at Highmark Stadium in an AFC East thriller. Live coverage begins at 7 PM ET on NBC and Peacock.

The Buffalo Bills will be the next NFL team to unveil their "Rivalries" uniform in Week 5. The Bills (4-0) host the New England Patriots (2-2) for an AFC East clash on "Sunday Night Football" at Highmark Stadium.

The unbeaten Bills host the improved Patriots on Sunday Night Football. Here's Sal Maiorana's preview of the game and his prediction.

The month of October and Week 5 of the 2025 NFL season have arrived, and the San Francisco 49ers treated the football world to a stunning 26-23 overtime road win over the Los Angeles Rams despite a depleted depth chart.

New England is coming off a confidence-building victory against the Carolina Panthers, 42-13. It was the franchise’s largest victory since Week 5 of the 2022 season. The Patriots hope those results can build confidence ahead of a primetime matchup against their toughest opponent.

FOXBORO — Three Patriots defensive starters are questionable to play Sunday night against the Bills.

USA Today's NFL experts make their picks for a Week 5 showdown between the Buffalo Bills and New England Patriots

Jason Logan breaks down his favorite Patriots vs. Bills same-game parlay ahead of Sunday Night Football from Highmark Stadium. Free NFL picks for October 5.

Defensive tackle Milton Williams returned to Patriots practice on Friday and the team is hopeful he'll be able to play on Sunday as well.

But that is predicated on Buffalo beating the Patriots, and with Maye and Stefon Diggs' Highmark Stadium return, who knows how things will play out. After all, Buffalo was close with the winless New Orleans Saints until the fourth quarter last week, so anything is possible.

The AFC-leading Buffalo Bills are off to a 4-0 start and have won 14 straight regular-season home games in preparing to host their division rival New England Patriots on Sunday night.