A broad-spectrum antiviral drug candidate, 2-thiouridine, that targets positive-strand RNA viruses has been identified and characterized. Positive-strand RNA viruses (ssRNA+ viruses) are a group of ...

Human norovirus, a positive-strand RNA virus that is the leading cause of viral gastroenteritis accounting for an estimated 685 million cases and approximately 212,000 deaths globally per year, has no ...

Norovirus is the leading cause of gastroenteritis and is responsible for hundreds of thousands of deaths every year. However, research progress into antiviral treatments and vaccines has been hindered ...

This study is reported by Xueping Zhou and Fangfangli’s group from the Institute of Plant Protection, Chinese Academy of Agricultural Sciences (IPP, CAAS), Beijing. Like other positive-sense ...

A 45-nucleotide strand of RNA can now synthesize both its mirror-image complement and a copy of itself, bringing scientists closer than ever to demonstrating how life could have emerged from chemistry ...

According to the RNA world hypothesis, life began when RNA molecules evolved the ability to make more copies of themselves. Now we have discovered an RNA molecule that is almost capable of this – it ...

Researchers at Washington University School of Medicine in St. Louis have identified central routes that two deadly viruses take to invade human cells and have designed decoy molecules that block the ...

Combining bioinformatics and experimetal approaches, researchers have discovered replication hubs for human norovirus, the leading cause of viral gastroenteritis accounting for an estimated 685 ...