Binding to RNA is not enough—changing its shape is what makes a drug work, study reveals

Ribonucleic acids (RNAs) serve as messengers between DNA and protein production, and perform a wide variety of regulatory functions across different cellular processes. This makes them an interesting ...
Science Daily

How an immune response is driven by one letter difference in DNA

One-letter difference in our DNA determines whether BCG vaccine provides good protection against tuberculosis or not. Researchers have elucidated how that one letter difference affects the activation ...
News Medical

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

In a recent study published in the Journal of American Medical Association (JAMA) Oncology, researchers from California investigated the diagnostic outcomes of concurrent sequencing of ...

Predicting RNA activity expands therapeutic possibilities

With AI, it's now possible for researchers to predict the three-dimensional structures of proteins directly from their ...
BioTechniques

DNA and RNA methylation directly linked for the first time

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...