Rheumatoid arthritis (RA) is a chronic autoimmune disease in which the immune system mistakenly attacks the lining of the joints (the synovium), causing pain, swelling, and progressive damage.

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA). IGFL2 is ...

Yi-Ping Li, Ph.D., Jay M. McDonald Endowed Professor in Bone Pathobiology, was recently awarded an R01 award from the National Institute of Arthiritis and Musculoskeletal and Skin Diseases titled, ...

The IGFL2 gene encodes a cytokine found in primates, which are closely related to humans. In the joint tissue of people with rheumatoid arthritis, peripheral helper T (Tph) cells express IGFL2, which ...