The San Francisco 49ers know what to expect from their star players, but if they want to compete in the NFC West, some second- and third-year players will need to break out.

San Francisco 49ers left tackle Trent Williams didn't hold back when discussing the team's Week 1 trip to Australia to face division rival Los Angeles Rams.

San Francisco 49ers offensive tackle Trent Williams didn't mince words about the Los Angeles Rams acquiring Myles Garrett in a blockbuster trade.

A team-by-team look at every NFC West win total, including why the Rams and 49ers could go over and why the Cardinals face a steep climb

The Los Angeles Rams will open the 2026 season in unconventional fashion, heading all the way to Melbourne, Australia for a Week 1 matchup with the San Francisco 49ers on Sept. 10. The game is still four months away but oddsmakers have already set betting lines for the season opener.

The San Francisco 49ers play the Los Angeles Rams in Week 1, and one member of Kyle Shanahan's team is already taking shots at their rival's fans.

As Los Angeles pairs Myles Garrett with a potential Aaron Donald comeback, the 49ers face a terrifying defensive gauntlet that threatens to upend the NFC West hierarchy.