G protein–coupled receptors (GPCRs) play crucial roles in the regulation of a wide variety of physiological processes and represent one-third of targets with clinically prescribed drugs. Yet, it ...
Receptor tyrosine kinases (RTKs) regulate many critical biological processes such as cell growth, differentiation, and survival through the recruitment of intracellular signaling molecules. The ...
Post-CAR T infection prophylaxis should follow European Hematology Association/European Society for Blood and Marrow ...
DuoCAR20.19.22-D95 targets CD19, CD20, and CD22, addressing antigen escape in B-cell malignancies like B-ALL and B-NHL. Early ...
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Omega-3 fatty acids regulate mammary gland lipogenesis and development via Gαs-mediated cAMP–EPAC signaling pathway
The research team found that the supplementation of n-3 fatty acids significantly enhances lactation performance even in ...
Expert Rev Mol Diagn. 2009;9(2):139-156. Diagnosis AIH-score > 15 AMA-M2 Elevated aP/γ-GT Compatible histology Cholangiography Elevated aP/γ-GT pANCA IBD γ-GT = γ-glutamyl transferase; AIH = ...
Yujun Wu, Yang Gao, Yanyan Zhan, Hong Kui, Hongyan Liu, Li Yan, Birgit Kemmerling, Jian-Min Zhou, Kai He, Jia Li Proceedings of the National Academy of Sciences of the United States of America, Vol.
Natural killer (NK) cells are lymphocytes of the innate immune system that are involved in the early defenses against foreign cells, as well as autologous cells undergoing various forms of stress, ...
A collaborative study on a plant intracellular immune receptor not only shows how an important resistance protein is activated during pathogen infection but also reveals some common operational ...
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