San Francisco was missing Brock Purdy, George Kittle and a slew of wide receivers but got huge performances from Mac Jones (342 passing yards, two touchdowns), Christian McCaffrey (139 total scrimmage yards) and Kendrick Bourne (10 catches, 142 yards).

The 49ers defeated the Rams 26-23 in overtime behind a terrific performance from Mac Jones, another workmanlike effort from Christian McCaffrey, a career night from Kendrick Bourne and several clutch red zone plays from their defense.

The San Francisco 49ers stayed atop the NFC West with a miracle win over the Los Angeles Rams in Week 5. Here are the highlights.

The Los Angeles Rams are taking on the San Francisco 49ers at home for the second week in a row. The Rams are currently undefeated at home afte

The 49ers took down the Rams in overtime in their Week 5 "Thursday Night Football" matchup. Here's how it happened.

The Rams escaped with a win over the Indianapolis Colts, whose self-destruction included Adonai Mitchell wiping out a game-winning touchdown on a holding penalty, dropping the ball before the goal line on a would-be touchdown,

Thursday Night Football for Week 5 renews an NFC West rivalry when the San Francisco 49ers head south to take on the Los Angeles Rams. These teams have dominated the division since 2017, winning seven of the past eight division titles combined. The 2017 season was also the first of Kyle Shanahan's and Sean McVay's tenures.

The Los Angeles Rams had a laundry list of mistakes in their 26-23 overtime loss to the San Francisco 49ers on Thursday night