The 49ers defeated the Rams 26-23 in overtime behind a terrific performance from Mac Jones, another workmanlike effort from Christian McCaffrey, a career night from Kendrick Bourne and several clutch red zone plays from their defense.

Follow along for live updates from the Los Angeles Rams' Week 5 game against the San Francisco 49ers on Thursday Night Football.

Los Angeles Rams inside linebacker Nate Landman (0:00), outside linebacker Byron Young (1:15), wide receiver Davante Adams (2:55), running back Kyren Williams (4:54), and wide receiver Puka Nacua (6:51) react to tonight's loss to the San Francisco 49ers.

San Francisco 49ers special teams swat away Los Angeles Rams K Joshua Karty's extra point attempt, keeping the game even.

The SportsLine projection model has revealed its Los Angeles vs. San Francisco picks for the 2025 NFL Week 5 'Thursday Night Football' game

Los Angeles Rams quarterback Matthew Stafford slings a 26-yard dot to wide receiver Davante Adams against the San Francisco 49ers at SoFi Stadium.