The San Francisco 49ers will be extremely shorthanded when they take on the Los Angeles Rams this Thursday night, that's for sure. Earlier this week, San Francisco ruled out starting quarterback Brock Purdy due to a lingering toe injury.

The San Francisco 49ers released their latest injury updates headed into the Week 5 contest versus the Los Angeles Rams.

The San Francisco 49ers will take on the Los Angeles Rams Thursday at SoFi Stadium. However, after this injury report, they'll be without key players.

A full-on quarterback controversy might not be brewing for the San Francisco 49ers, but after picking up his third win of the season, backup Mac Jones has certainly taken control of the conversation.

The San Francisco 49ers couldn't have a worse time to be down several key players with the NFC West division lead at stake.

The San Francisco 49ers head into Thursday Night Football against the Los Angeles Rams, with a 3-1 record, matching their division rivals. It’s a big early-season matchup, and the 49ers aren’t hiding anything,

San Francisco 49ers running back Christian McCaffrey was happy to escape with a hard-earned win over the Los Angeles Rams in Week 5.

The San Francisco 49ers completed the practice week on Friday for Sunday’s game against the Arizona Cardinals, and they released their final injury report. Their offensive depth is being tested. Quarterback Brock Purdy is not expected to play, while left guard Connor Colby was added to the report on Friday.

Those who wanted the Los Angeles Rams and San Francisco 49ers to battle in a high-scoring NFC West matchup in Week 5 may be in for disappointment.

Former 49ers safety Donte Whitner explains what San Francisco is missing on offensive without receiver Deebo Samuel.

The San Francisco 49ers pulled off a thrilling 26-23 overtime win against the Los Angeles Rams on Thursday Night Football. With Eddy Piñeiro’s 41-yard kick sealing the deal and the defence stopping Kyren Williams on fourth down,