Colorectal tumors that underwent somatic next-generation sequencing (NGS) for 154-168 genes in an in-house laboratory between 2015 and 2022 were retrospectively identified. Microsatellite instability ...

JCO Precision Oncology Conversations features discussions with leading authors of JCO Precision Oncology articles, hosted by Dr. Abdul Rafeh Naqash. Join our experts in engaging conversations as they ...

An international team of scientists has—for the first time, they suggest—systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to ...

Cancer is driven mainly by genomic instability, manifesting through a spectrum of somatic mutations that range from single nucleotide substitutions to large-scale chromosomal rearrangements, which ...

It's a fundamental principle of science: Correlation does not equal causation. Every cancer cell has genetic mutations, but not all of those mutations necessarily drive the cancer. A Harvard Medical ...

Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth. By testing every possible mutation in a critical hotspot, they found that ...

In this Innovation Spotlight, Peter Campbell, the cofounder and chief scientific officer of Quotient Therapeutics discusses a new somatic genomics platform built to identify these mutations and ...

Did you know that a simple genetic test called DNA testing is all that is needed to understand if you are at risk of ...

In a study published in Current Biology on August 14, Prof. Miao Wei's team at the Institute of Hydrobiology (IHB) of the Chinese Academy of Sciences and Prof. Zhang Jianzhi's team at the University ...