End-diastolic volume is the amount of blood that is in the ventricles before the heart contracts. Doctors use end-diastolic volume to estimate the heart’s preload volume and to calculate stroke volume ...
Cardiac pressor agents typically reduce the amount of blood pumped with each heartbeat. Cardiovascular hemodynamic principles can show whether such a response is physiologic or maladaptive. You have ...
The heart pumps blood against the mechanical afterload from arterial resistance, and increased afterload may alter cardiac electrophysiology and contribute to life-threatening arrhythmias. However, ...
A new model mimics physiologic loads on engineering heart muscle tissues, yielding an unprecedented view of how genetics and mechanical forces contribute to heart muscle function. Efforts to ...
The mainstay of medical management is pharmacotherapy, at the appropriate dose and combination, with drugs that have been shown to be effective in treating heart failure in large studies. As shown in ...
Adverse neurohormonal activation is an essential component in the pathogenesis of acute decompensated congestive heart failure (CHF). Consequently, blunting this activation is an important therapeutic ...
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