A team at UT Southwestern Medical Center has identified a structural trick that lets viruses translate their genetic code inside human cells, even when that code is riddled with “bad” codons the host ...

RNA viruses frequently bypass the conventional 5′ cap‐dependent mechanism of translation by employing alternative strategies that enable them to commandeer the host’s translational machinery. A ...

Platform combines proprietary AI sequence optimization, novel genetic parts, and lab validation in application-relevant cell models to improve expression and half-life, delivering top candidates in ...

Peptide conjugation techniques are advancing CNS delivery of oligonucleotides, addressing blood-brain barrier challenges and ...

An interdisciplinary research team from two working groups at the Center for Synthetic Biology at TU Darmstadt has developed ...

The vector consists of a polyethylene glycolylated liposomal outer coat (providing immune evasion and prolonged circulation), a spindle-shaped nanomotor (resembling a flagellum, facilitating targeted ...

Advances in genomics and RNA-based technologies are reshaping strategies for insect pest management by enabling the identification and exploitation of ...

A metabolic enzyme studied for over seven decades has a hidden second function - it can unwind RNA and promote cell cycle ...