Brain organoids, also known as brain spheroids, are three-dimensional cultures of neural cells derived from pluripotent stem cells (PSCs) that mimic the brain’s organization, development, and activity ...
eLife reviews research into cancer spanning from oncogenes and tumor suppressors to metastasis and anticancer treatments. Learn more about what we review and sign up for the latest research.
eLife reviews research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we review and sign up ...
Discussions around neurodiversity and neurodivergence in recent years have underscored the importance of listening to neurodivergent voices. With an emphasis on first-hand accounts, this collection ...
Crystal structures of Îł-protocadherin cell-cell recognition dimers reveal the determinants of clustered protocadherin homophilic specificity and cis interaction region structures alongside mutagenesis ...
where ΔG (γ = 0) is the free energy difference at zero tension, γ the membrane tension and ΔA the in-plane cross sectional area change associated with channel opening (Haswell et al., 2011). Thus, ...
eLife has changed its editorial process to eliminate accept/reject decisions after peer review and instead provide readers with richer and more nuanced assessments of articles. eLife changed its ...
Noticeable noises in the background, such as a phone ringing, shift our attention by activating the same circuit of nerves that we use when focusing on specific sounds. When walking into a busy ...
Add a comment + Open annotations. The current annotation count on this page is being calculated. People with certain blood types are more likely to have blood clots or bleeding conditions, kidney ...
This is a thorough, beautiful and compelling study of the flagellar structure of the choanoflagellate S. rosetta as reconstituted by cryo-electron tomography (now one of the handful of eukaryotic ...
Microbes often live in multispecies communities where interactions among community members impact both the individual constituents and the surrounding environment. Here, we developed a system to ...
These are nicely done and very complete studies which provide strong evidence that medullary collecting duct cells survive periodic medullary toxicity through upregulation of SLC38A2 , an amino acid ...
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