SANTA CLARA, Calif. — Pro Bowl left tackle Trent Williams and receiver Ricky Pearsall both missed practice Wednesday for the San Francisco 49ers, putting their status for the wild-card playoff game against the Philadelphia Eagles in question.

Kyle Shanahan says Trent Williams and Ricky Pearsall had a better chance to play if the Seahawks game was on Sunday.

As the San Francisco 49ers gear up for a crucial primetime showdown against the Seattle Seahawks, injury concerns loom large over the team's preparations. With significant postseason implications on the line, the final injury report released following ...

The Seahawks beat the 49ers to win the NFC West and the conference's top-seed. Here were the highlights and top plays!

The 49ers dropped huge news just before kicking off against the Seattle Seahawks. See how this will affect the biggest game of the year.

The San Francisco 49ers had a dreadful defensive showing, but they got a stop when it mattered while their offense continued rolling.