Follow along for live updates from the Los Angeles Rams' Week 5 game against the San Francisco 49ers on Thursday Night Football.

Los Angeles Rams inside linebacker Nate Landman (0:00), outside linebacker Byron Young (1:15), wide receiver Davante Adams (2:55), running back Kyren Williams (4:54), and wide receiver Puka Nacua (6:51) react to tonight's loss to the San Francisco 49ers.

The banged up San Francisco 49ers went into Sofi Stadium with back up quarterback Mac Jones and beat the Los Angeles Rams in overtime to kick off Week 5.

San Francisco 49ers defensive coordinator Robert Saleh, offensive coordinator Klay Kubiak, and quarterbacks Brock Purdy and Mac Jones addressed reporters following Thursday's practice as the team prepares for its Week 3 matchup against the Arizona Cardinals. Here's everything...

San Francisco 49ers special teams swat away Los Angeles Rams K Joshua Karty's extra point attempt, keeping the game even.

Los Angeles Rams quarterback Matthew Stafford's best throws from his three touchdown game vs. the San Francisco 49ers during Week 5 of the 2025 NFL season.

On a night to remember, here are the three players who were graded the highest in San Francisco's overtime win against Los Angeles

The Jacksonville Jaguars are now officially 3-1, after a 26-21 victory over the San Francisco 49ers on the road. Running back Travis Etienne paved the way to victory, recording 124 yards on the ground, including a 48-yard touchdown run to put the Jags on the board.

JUMP TO: 49ers vs. Rams score 49ers vs. Rams highlights Where to watch 49ers vs. Rams Week 5 of the 2025 NFL season begins with the San Francisco 49ers making the trip to Inglewood, California,

Jacksonville Jaguars Travis Etienne Jr. took it the distance for a 48-yard touchdown against the San Francisco 49ers.