Former New York Jets quarterback Adrian Martinez signed with the San Francisco 49ers following the Brock Purdy injury news.

On Thursday night, the former No. 1 pick continued his strong start for the 49ers, providing more confirmation of what has been seen in other NFL cities.

Here is a closer look at the 49ers' injuries, how the team has been impacted in comparison to other NFL franchises and a year-by-year timeline of absences to key players.

What happened: The 49ers jumped out to a 20-0 halftime lead in their Super Bowl debut and then held on for dear life. They forced four turnovers, including a squib kick fumble by Archie Griffin just before halftime that led to the second of four Ray Wersching field goals.

To replace those departed contributors, the 49ers focused on the 2025 NFL draft and rebuilding their defense. It was a roster reimagining following a similar blueprint of the 2023 Los Angeles Rams and 2024 Buffalo Bills, both teams that Lynch says his staff spent time studying before the offseason began.

Los Angeles Rams wide receiver Puka Nacua hit an NFL milestone on "Thursday Night Football" against San Francisco 49ers.

San Francisco 49ers quarterback Brock Purdy has featured in just two games this season due to a toe injury, but the team has not missed him, thanks to backup Mac Jones' resurgence, who has led the tea

Los Angeles Rams defensive end Tyler Davis discusses the defense's success in stopping opponents' run game over the past 4 weeks, working with the same trainer as nose tackle Poona Ford, and more.

San Francisco 49ers quarterback Brock Purdy could miss additional games after aggravating his toe injury last week, NFL Network's Ian Rapoport reports.Purdy, who's inactive Thursday against the Los Angeles Rams,