Not only were the 49ers missing Purdy, Nick Bosa (who is out for the season with a torn ACL) and star tight end George Kittle ...

Missing a plethora of key starters, back-up quarterback Mac Jones led the depleted San Francsico 49ers to a thrilling 26-23 overtime victory over the Los Angeles Rams on Thursday Night Football.

The San Francisco 49ers stayed atop the NFC West with a miracle win over the Los Angeles Rams in Week 5. Here are the ...

Kyren Williams fumbles the ball at the goal line late in regulation and can't convert on fourth down in overtime in the Rams' ...

The 49ers defeated the Rams 26-23 in overtime behind a terrific performance from Mac Jones, another workmanlike effort from ...

San Francisco was missing Brock Purdy, George Kittle and a slew of wide receivers but got huge performances from Mac Jones ...

The Arizona Cardinals play the San Francisco 49ers in a game on the NFL Week 3 schedule on Sunday, Sept. 21, at the 49ers' Levi's Stadium in Santa Clara, California. Here's a look at the time, TV ...

Week 2 of the 2025 NFL season continues with the San Francisco 49ers traveling to Caesars Superdome to take on the New Orleans Saints on Sunday. Here's what you need to know about how to watch the ...

The San Francisco 49ers are dealing with a rash of injury issues entering their Week 2 matchup with the New Orleans Saints. Head coach Kyle Shanahan on Monday spoke with reporters on a conference call ...