In contrast to cohesin, which binds two sister chromatids together, condensin is thought to bind a single chromatid at multiple spots, twisting the chromatin into a variety of coils and loops ...

Science DNA breaks are toxic lesions for the cell. In order to repair these breaks, it is necessary, starting from the break ends, to find a homologous sequence within the vastness of the genome. In ...

Each chromosome is, at this time, actually two identical copies. Each copy is called a chromatid. A spindle begins to form from the centrioles. This spindle is made of fibers. The centrioles begin ...

During anaphase II, microtubules from each spindle attach to each sister chromatid at the kinetochore. The sister chromatids then separate, and the microtubules pull them to opposite poles of the ...

This rigorous and practical account of the interpretation of mutagenicity test data draws upon the expertise of toxicologists and statisticians. Chemicals, such as drugs, food additives and pesticides ...