SERIES RECORD: 49ers lead 19-14-1. LAST MEETING: 49ers defeated the Eagles 17-11 on Sept. 9, 2021, in Philadelphia. LAST WEEK: 49ers defeated Cowboys, 19-12; Eagles beat Giants, 38-7. EAGLES OFFENSE: OVERALL (3), RUSH (5), PASS (9), SCORING (3). EAGLES ...

The San Francisco 49ers are visiting the Los Angeles Rams for a Thursday Night Football showdown in Inglewood. Here's how to watch:

While several teams fell from the ranks of the undefeated Sunday, Philadelphia won its 18th straight game with Jalen Hurts under center.

Thursday Night Football, Week 5. Tonight we have a clash of NFC West rivals as the Los Angeles Rams host the San Francisco 49ers.

Week 5's Thursday Night Football matchup between the Rams and 49ers will air live on Amazon Prime Video. The action will not be available on traditional TV. NFL fans can tune into the Rams vs. 49ers game live on SiriusXM channels 225 (Rams) and 226 (49ers).

It was a slow start for Baker Mayfield and his Tampa Bay Buccaneers on Sunday. In a battle of unbeatens between the Philadelphia Eagles and the Tampa Bay Buccaneers, Philadelphia scored two early touchdowns to take a 14-0 lead. Mayfield was unable to get the offense going, and the absence of veteran receiver Mike Evans appeared to loom large early.

San Francisco 49ers quarterback Brock Purdy is once again dealing with a toe issue after returning to the lineup on Sunday.

Jones threw for 342 yards and two touchdowns in the performance as the 49ers advanced to 4-1 on the season. San Francisco has now beaten all three of its divisional opponents in the 2025 season.