NFL survivor pool strategy, predictions and picks for ESPN Eliminator Challenge Week 5, including teams to pick or save for later.

In our Week 5 picks against the spread, Philadelphia does more flexing against a 2024 playoff team vs. Denver, while Kansas City stymies an AFC upstart and Dallas doesn't settle for a tie back in New York.

Fading the Titans each week is proving to be a solid strategy, and the Arizona Cardinals should be ready to rebound at home.

Ferguson has totaled at least seven receptions in each of his past three games. He can stretch the seams, but the majorly of his production has been on underneath throws from Dak Prescott. Ferguson is a zone outlet here, which means high-percentage targets to cash in on this week. -- Bowen

Mike Florio is picking the Chiefs to win by eight points, while Chris Simms is picking Kansas City to win by three points. "The Chiefs are back, and the Jaguars are too inconsistent," Florio wrote. A clean sweep from the Monday Morning Quarterback crew, with all seven staff members picking the Chiefs.

Better known as 'Prop Bet Guy,' Kralstein specializes in NFL props, and he enters Week 5 on a 27-15 run on NFL player props that has returned more than $1,000 for $100 bettors. One of his top prop picks this week is going Over 13.5 total receiving yards for Houston Texans running back Woody Marks (-114).

Week 5 in the NFL starts with a must-see Thursday Night Football matchup between the San Francisco 49ers and the Los Angeles Rams.

Bowen and Seth Walder bring different perspectives to how they approach sports betting. A former NFL safety, Bowen predicts positive matchups and game winners from tape study and his understanding of the league. Walder relies on statistical models to pick out plus-expected value bets.

Now, the model, which simulates every NFL game 10,000 times, has revealed its Fantasy football rankings for Week 5 of the 2025 NFL season. Head to SportsLine now to see them .