Hexokinases regulate the metabolic transcription factor MML-1 via distinct pathways, linking glucose metabolism and organellar signaling to longevity control in Caenorhabditis elegans and mammals.

A high-throughput chemical screen identifies ligands of the Kelch domain of E3 ligase KLHDC2 capable of being modified as proteolysis-targeting chimeras.

In this preregistered study, Kunkel and colleagues set out to compare the magnitude and duration of placebo versus nocebo effects in healthy volunteers, and also to examine the different factors ...

This study reveals that female moths utilize ultrasonic sounds emitted by dehydrated plants to inform their oviposition decisions, highlighting sound as a potential sensory cue for optimal host plant ...

New morphological information on the Cambrian artiopodan Acanthomeridion, including CT data, demonstrate that dorsal ecdysial sutures likely evolved multiple times within this group.

Novel genetic fate-mapping strategies enabled re-analysis of cortical oligodendrocytes derived from dorsal pallium, LGE/CGE, and MGE/POA, challenging the canonical view of substantial LGE/CGE ...

By explaining how a lab works, outlining what is expected of everyone, and describing the culture the lab is aiming for, a good lab handbook will benefit all the members of a research group.

Offering users reaction buttons that convey reliability (e.g., ‘trust’, ‘distrust’) increases discernment and significantly reduces the spread of misinformation on a social media platform.

The lifespan of individuals who suffer from an osteoporotic fracture is reduced by between 1 and 7 years, depending on the location of the fracture and their risk profile, suggesting that their ...

The combination of the MS2 system with the Suntag system as a signal amplifier allows enhanced single-molecule mRNA imaging in live cells and animals.

The first recently discovered inhibitors of lysine biosynthesis with in planta activity have a dual-target mode of action, which provides proof-of-concept for the development of multi-target ...

During human running, the soleus muscle was found to operate as work generator under optimal conditions for work production (high force-length potential and enthalpy efficiency) while the vastus ...