Background Advances in systemic therapy for advanced hepatocellular carcinoma (HCC) have fuelled a growing interest in ...

Background Hospitalisations represent major clinical events in cirrhosis, yet prediction based on clinical variables alone ...

Metastatic pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest solid cancers, portending poor patient outcomes ...

Background The liver naturally exhibits robust glycosylation processes, yet how aberrant glycosylation affects hepatocellular carcinoma (HCC) and its underlying mechanisms remains poorly understood.

3 Department of Internal Medicine, Ullevål University Hospital, Oslo, Norway 4 Department of Internal Medicine, Diakonhjemmet Hospital, Oslo, Norway 5 Department of Internal Medicine, Telemark ...

Objective SETD2, the sole histone H3K36 trimethyltransferase, is frequently mutated or deleted in human cancer, including pancreatic ductal adenocarcinoma (PDAC). However, whether SETD2/H3K36me3 ...

4 Department of Hepatogastroenterology, Hopital Claude Huriez, CHRU Lille, France Correspondence to: Professor J-F Colombel Department of Hepato-Gastroenterology, Hopital Claude Huriez, CHRU de Lille, ...

1 Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University 2 Department of Human Pathology, Graduate School of Medical and Dental Sciences, ...

Department of Surgery, Duke University Medical Center and Veterans’ Administration Hospital, Durham, NC, USA Correspondence to: Dr C R Mantyh, Duke University Medical Center, Box 3117, Durham, NC ...

Correspondence to: Professor J Dent Department of Gastroenterology, Hepatology, and General Medicine, Level 7, North Wing, North Terrace, Royal Adelaide Hospital, Adelaide, South Australia 5000, ...

Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, has multifactorial aetiology with complex interactions between genetic and environmental factors. Over 150 ...