Sparsentan lowered blood pressure more than irbesartan at week 8, with mean differences of -7.2 mmHg systolic and -5.6 mmHg diastolic.

Praliciguat alone or with enalapril as background therapy in a mouse model of primary FSGS and a rat model of secondary FSGS showed that praliciguat alone offered no benefit.

Clinically approved drugs induced ChAT expression and acetylcholine production in podocytes in vivo, suggesting the pathway could be pharmacologically targeted.

Bodily pain, vitality, and general health perceptions showed stronger associations with quality of life at lower proteinuria thresholds.

Across all patients, higher urinary CD93 was strongly associated with a faster time to a 40% decline in eGFR and a faster time to kidney failure.

An observational study found that living in neighborhoods with high urban heat intensity reduces the chances of textbook surgical recovery.

Surveillance strategies following surgery for non-clear cell renal cell carcinoma (nccRCC) may need to differ from clear cell RCC.

Undeclared pharmacologically active ingredients (UPAIs) are detected in one-third of over-the-counter (OTC) skin products marketed online, according to a stud ...

Investigators evaluated outcomes after endoscopic kidney-sparing surgery for upper tract urothelial carcinoma (UTUC).

Seven percent of participants had an eGFR of 30 to 60 mL/min/1.73 m2, and 40% had an eGFR of 60 to 90 mL/min/1.73 m2 (HealthDay News) — For adults taking potassium-raising medications, greater ...

Compared with other diagnostic methods, superior performance was seen in FAST in a sensitivity analysis of head-to-head studies. (HealthDay News) — FibroScan-aspartate aminotransferase (FAST) ...

Keisha L. Gibson, MD, MPH, is a physician scientist and the division chief of Pediatric Nephrology department at UNC School ...