The 49ers defeated the Rams 26-23 in overtime behind a terrific performance from Mac Jones, another workmanlike effort from Christian McCaffrey, a career night from Kendrick Bourne and several clutch red zone plays from their defense.

The San Francisco 49ers beat the Los Angeles Rams in what looked like an improbable outcome. San Francisco was far more shorthanded than their division rivals due to injuries, but still pulled off the upset. While the team is going to be happy with the win, they will have to evaluate a new slew of injuries .

The injury-ravaged San Francisco 49ers will again be missing multiple starters with injuries for the Thursday night game against the Los Angeles Rams.

San Francisco 49ers quarterback Brock Purdy is officially out for "Thursday Night Football" against the Los Angeles Rams with a toe injury. Mac Jones is expected to start in Purdy's place.

The San Francisco 49ers ruled Purdy out for Thursday’s matchup with the Los Angeles Rams officially on Wednesday afternoon due to a toe injury. That paves the way for backup Mac Jones, who has won a pair of games already this season filling in for Purdy, to get the start at SoFi Stadium.

Eagles WR A.J. Brown is publicly frustrated with the team about his lack of targets. Could the 49ers acquire him with this trade package?