Mac Jones threw three touchdown passes in place of Brock Purdy and the 49ers improved to 2-0 with a 26-21 win at New Orleans ...

Kickoff from Caesars Superdome is set for 1 p.m. ET. San Francisco is a 3-point favorite in the latest 49ers vs. Saints odds from SportsLine consensus, while the over/under for total points scored is ...

If they're smart, the 49ers would trade for a young edge rusher who could fill the roster hole left by Bosa this season but also play alongside him for years to come. John Sigler ...

The Saints just spent a second-round pick on Tyler Shough, so theoretically, they've already made a draft-capital investment ...

The NFL has made a major schedule change, flexing the 49ers-Buccaneers into a late slot and pushing down Patriots-Saints.

Sigler projected the 0-4 Saints to quickly become sellers ahead of the Nov. 4 trade deadline. One of his potential moves has ...

The San Francisco 49ers were recently dealt a crushing injury blow, as their superstar defensive end Nick Bosa was diagnosed ...

Rod Walker paints the scene as the Dome, especially the Saints' loss to the 49ers, has lost a bit of its swagger.

Mac Jones passed for 279 yards and a career-high-tying three touchdowns, and the banged-up San Francisco 49ers defeated the ...

The New Orleans Saints added another piece to the practice squad on Thursday. This time, the player coming through the door ...

The San Francisco 49ers defeated the Los Angeles Rams in Week 5 with a 26-23 "Thursday Night Football" win at SoFi Stadium.

The San Francisco 49ers have promoted defensive lineman Robert Beal Jr. to the active roster from the team's practice squad ...