No relapses occurred in patients whose MPO-ANCA levels decreased and remained negative, corresponding to a negative predictive value of 100%. In patients with antineutrophil cytoplasmic antibody (ANCA ...

Ear, nose and throat (ENT) manifestations are an important hallmark of inflammatory rheumatic diseases, varying from mild to life-threatening manifestations. They can be the first symptoms or occur ...

In the GPA subgroup, organ damage (except ENT) was more frequent among patients who were seropositive. Conversely, in the MPA and EGPA groups, skin, ENT, and joint involvement were more common in ...

The body’s defence (immune) system fights injury or infection by sending white blood cells to surround and protect the affected area. This causes redness and swelling, called inflammation. Vasculitis ...

Patients with ANCA-associated vasculitis who received avacopan had lower exposure-adjusted rates of adverse events, infections, and neutropenia/lymphopenia. Among ...

Avacopan was safe and effective among patients with respiratory tract manifestations of antineutrophil cytoplasmic antibody-associated vasculitis. Avacopan shows promising efficacy and safety among ...

In 2019, the age-adjusted prevalence for vasculitis per 1,000,000 Alaska Native and American Indian adults was 752 (95% CI, 581-959). The prevalence of antineutrophil cytoplasmic antibody-associated ...

Avacopan was safe and effective among patients with respiratory tract manifestations of antineutrophil cytoplasmic antibody-associated vasculitis. Researchers performed a post hoc analysis of the ...

Anca Inc. launches Anca Academy, a new e-Learning platform for their customers, designed to elevate skills in operating Anca CNC machines and application software. Offering a mix of free and paid ...

Objective To compare the efficacy and safety of alternative glucocorticoids (GCs) regimens as induction therapy for patients with antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis.

Necrotizing and crescentic glomerulonephritis arises in all 3 AAV subtypes: GPA, MPA, and EGPA. According to findings from a study recently published in the journal Kidney International, among ...

Ocular manifestations are common among patients with all types of antineutrophil cytoplasmic antibody-associated vasculitis, and machine learning-based predictive models offer potential for early ...