Buffalo Bills vs New England Patriots
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The Falcons have seen a tremendous year-over-year improvement from their defense, but their post-bye week showdown with the Bills will be its biggest test yet.
Will Drake Maye and the Patriots hand the Bills their first loss in Stefon Diggs' return to Buffalo? Which running backs are primed for big outings? Our analysts provide bold predictions for Week 5 of the 2025 NFL season.
It's a busy uniform slate in Week 5 of the NFL season, led by the Buffalo Bills debuting their Rivalry threads.
The Buffalo Bills have a chance to go 3-0 in the division early on when they host the New England Patriots in what looms to be a tough outing with Stefon Diggs making his return to Highmark Stadium.
The Buffalo Bills focus on defense once again in this 3-round 2026 NFL mock draft, landing two new starters with their first couple of selections.
Entering the season, it appeared as though the top-heavy AFC would be a three-team fight to the finish, but with the 1-3 Ravens and 2-2 Chiefs off to uncharacteristically slow starts, Buffalo now looks like the class of the conference all by itself. And winning the conference could make a world of difference once the Bills reach the postseason.
16hon MSN
NFL Week 5 bold predictions: Drake Maye's Patriots hand Josh Allen's Bills first loss of 2025
The month of October and Week 5 of the 2025 NFL season have arrived, and the San Francisco 49ers treated the football world to a stunning 26-23 overtime road win over the Los Angeles Rams despite a depleted depth chart.
Did Buffalo Bills Coach Sean McDermott tell the press that he will pull his team from the 2026 Super Bowl because of the National Football League's choice to make Bad Bunny the 2026 halftime performer?