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Study finds no safety or efficacy gap between paracetamol and ibuprofen for neonatal PDA

In a UK pilot randomized trial, intravenous paracetamol and ibuprofen showed no statistically significant differences in short-term efficacy or safety when used as rescue therapy for hemodynamically ...

FDA Granted Hopstem’s hNPC01 for Chronic Ischemic Stroke Approval to Enter Phase 2/3 Adaptive Pivotal Clinical Trial with Bridging Study

The approval of this accelerated pathway not only demonstrates the FDA’s full recognition of the quality, safety, and efficacy of the Phase 1 clinical data of hNPC01 in China, but also will ...

Groundbreaking Remote Clinical Trial Shows GABA-Producing Probiotic Improves Sleep and Reduces Stress

People Science, a leader in decentralized clinical research, today announced the publication of a clinical study conducted with Verb Biotics in Nature Scientific Reports. The peer-reviewed trial ...

Levee Medical(R) Announces Landmark ARID II Trial Nears Halfway Enrollment Milestone and Publication of ARID Clinical Results in World Journal of Urology

Levee Medical(R) , a medical device company focused on improving outcomes for prostate cancer surgery patients, today announced continued progress in the clinical and commercial advancement of its ...
Ophthalmology Times

SpyGlass Pharma randomizes first patients in 2 phase 3 clinical trials of the BIM-IOL System

SpyGlass Pharma has randomized the first patients in its 2 registrational phase 3 clinical trials of the Bimatoprost Drug Pad-IOL System (BIM-IOL System) for the lowering of intraocular pressure (IOP) ...
BMJ Open

Hydroxychloroquine as an adjunct therapy in the management of type 2 diabetes in pregnancy: study protocol for a randomised controlled trial

Introduction The increasing incidence of type 2 diabetes mellitus (T2DM) among women of reproductive age poses significant health risks for both mothers and their fetuses. Optimising blood glucose ...

Corvus Pharmaceuticals Announces Positive Data from Cohort 4 Confirming Results for Placebo-Controlled Phase 1 Clinical Trial of Soquelitinib for Atopic Dermatitis

Cohort 4 data demonstrated positive safety and efficacy results, including additional clinical benefit observed following ...

Insurance data can help fill gaps between longer medical trials for patients up against the clock

Randomized clinical trials remain the gold standard for establishing a medication's effects, producing the evidence by which ...
The New York Times

What Are Clinical Trials, and How Do They Work?

A New York Times health reporter explains what clinical trials are, why they are important and how they can help inform us. Credit...Ricardo Tomás Supported by By Nina Agrawal Nina Agrawal is a health ...
ebm.bmj

Efficacy of open-label placebos for premenstrual syndrome: a randomised controlled trial

Objective To investigate the efficacy and safety of open-label placebos (OLP) in premenstrual syndrome (PMS). Design Randomised controlled trial. Setting Switzerland, 2018–2020. Participants 150 women ...
Business Wire

Journal of the American Medical Association (JAMA) Publishes Results from First-Ever Randomized, Placebo-Controlled Clinical Trial Assessing the Dose-Dependent Efficacy of ...

The Phase 2b study demonstrated a statistically significant dose-response relationship at the primary endpoint following a single administration of MM120 across four dose levels, with improvements ...