The Colts vs. Rams game kicks off at 4:05 p.m. ET/1:05 p.m. PT this Sunday, Sept. 28, 2025. The Week 4 game between the Colts and the Rams will air locally on FOX. Out-of-market, you can tune in via NFL Sunday Ticket on YouTube TV.

The Indianapolis Colts released their Friday injury report and Michael Pittman Jr. was off it and should be good to go against the Raiders.

Here is everything you need to know about the Colts vs. Broncos, including TV and streaming options for the Week 2 NFL game.

The Indianapolis Colts blast the Miami Dolphins in NFL Week 1 action: Live score updates, stats, highlights, injuries.

INDIANAPOLIS -- Indianapolis Colts defensive coordinator Lou Anarumo didn't try to defend it. Having just 10 defenders on the field during a critical moment in Sunday's game against the Los Angeles Rams was a costly mistake that cannot be minimized, and Anarumo made no effort to do so.

Indianapolis Colts cornerback Xavien Howard announced his retirement from football just four games into the NFL season. In a statement on Wednesday, Oct. 1, Howard said he's 'no longer willing' to put football over family.

"Anytime you're playing a guy with elite contact balance and skill like Jeanty, you gotta get 11 hats to the ball," added linebacker Zaire Franklin. "We're taught 11 vs. 1, it's not one of us versus (Jeanty), it's all of us versus whoever has the ball."